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Citalopram-hypericum

678 bytes added, 12:08, 7 May 2009
Created page with '{{ Drugswitch | from = citalopram | to = hypericum | stop = * '''Before day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day, resp. 10 mg/day...'
{{ Drugswitch
| from = citalopram
| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day, resp. 10 mg/day.
* '''Day 1:''' reduce dosage of citalopram/escitalopram to 10 mg/day, resp. 5 mg/day.
* '''Day 8:''' stop administration of citalopram/escitalopram.
| start =
* '''Day 8-14:''' a wash-out period of one week is necessary.
* '''Day 15:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Hypericum slows the metabolism of citalopram/escitalopram via CYP3A4. }}
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