838
edits
Changes
Created page with '{{Drugswitch | from = clomipramine | to = trazodone | stop = * '''Before day 0:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/ day, when this dosage is > 5...'
{{Drugswitch
| from = clomipramine
| to = trazodone
| stop =
* '''Before day 0:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 8:''' stop administration of clomipramine.
| start =
No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.
* '''Day 8:''' continue only administration of trazodone. If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}
| from = clomipramine
| to = trazodone
| stop =
* '''Before day 0:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 8:''' stop administration of clomipramine.
| start =
No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.
* '''Day 8:''' continue only administration of trazodone. If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}