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* '''Day 0:''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
* '''Day 1:''' reduce a dosage of 30 mg/day to 15 mg/day.
* '''Day 8:''' stop administration of mirtazapine.
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* '''Day 18:''' simultaneously start fluvoxamine in a normal dosage of 50 mg/day.* '''Day 8:''' stop administration of mirtazapine and only continue administration If necessary, increase dosage of fluvoxamine in a dosage of to 50-100 mg/day.
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* Caution with this switch is necessary, because fluvoxamine slows the metabolism of mirtazapine via CYP1A2, CYP3A4 and CYP2D6.}}
