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Tranylcypromine-clomipramine

93 bytes removed, 15:51, 30 June 2023
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| to = clomipramine
| stop =
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached, stop administration.{{stopTranyl}}
| start =
* '''Day 1-14:''' a wash-out period of two weeks is necessary. {{28Inc25p3d}} <ref name="informatorium">{{KNMP|tranylcypromine}}</ref> * '''Day 15:''' start clomipramine after this period in a low dosage of 25-50 mg/day.|caveat ={{caveSS}}
| info =
* Occurrence of the serotonin syndrome is possible without a wash-out period.{{Tcrestore}}<ref name="informatorium">{{KNMP|tranylcypromine}}</ref> * The wash-Tranylcypromine has to be phased out period is necessary for the MAO enzymes to restore their functionavoid withdrawal symptoms.<ref>Dr. M.J.Blom et al.(2009) Gebruik van klassieke MAO-remmers</ref>{{TCAplasmalevelmonitoring}} }}

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