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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 30 mg/ day. When a dosage of 30 mg/day is reached, stop administration.
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A wash-out period of one week two weeks is necessary. * '''Day 1-713:''' wash-out period* '''Day 814-1421:''' start tranylcypromine at half the usual dosage for one week, 20 mg/day. * '''Day 1522:''' increase dosage of tranylcypromine if necessary.
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* By considering a wash-out period of one week (5 times the elimination time of duloxetine and its metabolites) it is assured that all duloxetine has left the body and no drug interactions occur. }}
