* '''Before day 0:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 40 mg/day, resp. 20 mg/day.
* '''Day 1:''' reduce dosage of citalopram/escitalopram to 20 mg/day, resp. 10 mg/day.
* '''Day 8:''' reduce dosage of citalopram/escitalopram to 10 mg/day, resp. 5 mg/day.* '''Day 15:''' stop administration of citalopram/escitalopram.
| start =
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.
* '''Day 158:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. }}