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Dosulepine-paroxetine

58 bytes removed, 10:26, 13 July 2009
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* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.
* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.
* '''Day 7:''' stop administration of dosulepine
| start =
* '''Day 18:''' simultaneously start administration of paroxetine in a normal dosage of 20 mg/day.* '''Day 8:''' stop administration of dosulepine and continue administration of paroxetine.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes dosulepine. }}
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