* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.
* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.
* '''Day 7:''' stop administration of dosulepine.
| start =
* '''Day 18:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.* '''Day 815:''' stop administration of dosulepine and continue administration of sertraline in a dosage of 50-100 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Sertraline is a weak inhibitor of CYP2D6, which metabolizes dosulepine. }}