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* '''Day 15-22:''' a wash-out period of one week is necessary.
* '''Day 23:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info caveat = * Occurrence of the serotonin syndrome is theoretically possible, so caution is necessarywithout wash-out period.* Hypericum slows the metabolism of imipramine via CYP3A4. | info ={{HypericumInfo}} }}
