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Venlafaxine-clomipramine

343 bytes removed, 15:58, 17 July 2009
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| to = clomipramine
| stop =
* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.{{downVenla}}
| start =
* '''Day 115:''' simultaneously start administration of clomipramine in a low dosage of 25-50 mg/day. * '''Day 8:''' stop administration of venlafaxine and continue administration of clomipramine in a dosage of 50-75 mg/day.
| info =
* “Start low, go slow” for clomipramine, and caution with this switch is necessary.
* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes clomipramine.}}
Walter
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