* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.
* '''Day 3:''' reduce dosage of maprotiline to 25 mg/day.
* '''Day 7:''' stop dosage of maprotiline.
| start =
* '''Day 1:''' simultaneously start administration of venlafaxine in a normal dosage of 75 mg/day.* '''Day 8:''' stop administration of maprotiline and continue administration of venlafaxine.{{startVenla}}| info caveat =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}