No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of trazodone in a dosage of 100-150 mg/day.
* '''Day 8:''' continue only administration of trazodone. If necessary, increase the dosage every 3-4 daysof days of trazodone to a maximum of 400 mg/day.
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* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}