| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of imipramine according to the scheme above.
* '''Day 8:''' stop administration of imipramine and continue administration of bupropion only in a dosage of 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes imipramine. }}