No wash-out period is needed.
* '''Day 1:''' start mirtazapine the next day in low dosage of 15 mg/day for one week.
* '''Day 821:''' increase dosage of mirtazapine to normal, 30 mg/day.
| info =
* (Desmethyl)Fluoxetine has a very long elimination time; phasing out fluoxetine is therefore not necessary. * Fluoxetine slows the metabolism of mirtazapine through CYP2D6.}}