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Duloxetine-doxepine

85 bytes removed, 08:01, 4 August 2009
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* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.
* '''Day 8:''' stop administration of duloxetine.
| start =
No wash-out period is needed.* '''Day 18:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.* '''Day 815:''' stop administration of duloxetine and increase the dosage of doxepin to 50 mg/day.
| info =
* Duloxetine slows the metabolism of doxepin by CYP2D6.
* Caution is necessary at the start of administration of doxepin. {{theorSS}}}}
Walter
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