* '''Day 8:''' stop administration of doxepin
| start =
* '''Day 18:''' simultaneously start administration of duloxetine in a normal dosage of 60 30 mg/day.* '''Day 815:''' stop administration of doxepin and continue increase administration of duloxetineto 60 mg.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Duloxetine is a inhibitor of CYP2D6, which metabolizes doxepin.}}