* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.
* '''Day 3:''' reduce dosage of doxepin to 25 mg/day.
* '''Day 8:''' stop administration of doxepin.
| start =
* '''Day 18:''' simultaneously start administration of fluoxetine in a normal dosage of 20 mg/day.* '''Day 8:''' stop administration of doxepin and continue administration of fluoxetine.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Fluoxetine is a strong inhibitor of CYP2D6, which metabolizes doxepin. }}