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Doxepine-paroxetine

128 bytes removed, 12:23, 5 August 2009
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* '''Before day 0:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.
* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.
* '''Day 38:''' reduce dosage of doxepin to 25 mg/day.* '''Day 15:''' stop administration of doxepin.
| start =
* '''Day 115:''' simultaneously start administration of paroxetine in a normal dosage of 20 mg/day.* '''Day 8:''' stop administration of doxepin and continue administration of paroxetine.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}
* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes doxepin. }}
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