* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.
* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.
* '''Day 38:''' reduce stop dosage of amitriptyline to 10 mg/day.
| start =
* '''Day 18:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.* '''Day 815:''' stop administration of amitriptyline and continue administration if necessary, increase dosage of sertraline.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}}}