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* Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
* Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.
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* Day 81: no wash-out period is needed. Start simultaneously start administration of imipramine maprotiline in a low normal dosage of 25-75 mg/day. * Start low, go slow!Day 8: stop administration of citalopram/escitalopram and continue administration of maprotiline only.
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* “Start low, go slow” for maprotiline is not required, but caution is necessary.
* The same applies to [[escitalopram]].
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