Changes

* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.

| start =

* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.

* '''Day 8:''' stop administration of fluvoxamine and continue administration of maprotiline. If necessary, increase dosage of maprotiline.