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| to = duloxetine
| stop =
* '''Before day Day 0:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/day.* '''Day 1-7:''' reduce dosage of clomipramine to 25 mg/day.* '''Day 78:''' stop dosage administration of clomipramine.
| start =
* '''Day 108-14:''' a wash-out period of one week is necessary.* '''Day 15:''' start administration of duloxetine in a normal dosage of 60 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Duloxetine is an inhibitor of CYP2D6, which metabolizes clomipramine.
}}
