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{{Drugcombi
| base = carbamazepineCarbamazepine| add = risperidoneOlanzapine
| info =
* more information when adding risperidone to carbamazepineCarbamazepine is principally metabolized by CYP3A4 (also CYP2C8), but is also a potent inducer of CYP1A2, CYP3A4 and UDP-glucuronosyltransferases.* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.| start =* start precautions Carbamazepine can reduce olanzapine serum concentration, possible below therapeutic range. Add olanzapine according to the general dosing advice and increase dose based on clinical effect or serum concentration. <ref name=”medicatiebewaking”> Schalekamp T. et al, Interacties met Psychofarmaca, Stichting Health Base, Houten, 2002. </ref> <ref name=”levyrh”> Levy RH et al, Metabolic Drug Interactions, Lippincott Williams & Wilkins, Philadelphia, 2000. </ref> <ref name=”bazire”> Bazire S, Pshychotropic Drug Directory 2007, HealthComm UK Limited, Aberdeen, 2007. </ref>| stop cave =* stop precautions
}}
