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Created page with '{{Drugcombi | base = Lamotrigine | add = Lithium | info = * Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases. * Lithium is eliminated by the kidney for ab...'
{{Drugcombi
| base = Lamotrigine
| add = Lithium
| info =
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Lamotrigine does not cause a significant change in the pharmacokinetics of lithium. <ref> {{Pubmed| 10971302 |Chen C at al, The effects of lamotrigine on the pharmacokinetics of lithium. Br J Clin Pharmacol 2000;50(3):193-5}}</ref>
| cave =
}}
| base = Lamotrigine
| add = Lithium
| info =
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Lamotrigine does not cause a significant change in the pharmacokinetics of lithium. <ref> {{Pubmed| 10971302 |Chen C at al, The effects of lamotrigine on the pharmacokinetics of lithium. Br J Clin Pharmacol 2000;50(3):193-5}}</ref>
| cave =
}}
