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Combining-Lamotrigine-Carbamazepine
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14:08, 4 March 2010
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{{Drugcombi
| base =
Lamotrigine
lamotrigine
| add =
Carbamazepine
carbamazepine
| info =
*
Lamoptrigine
Lamotrigine
is principally metabolised by UDP-glucuronosyltransferases.
* Carbamazepine is principally metabolized by CYP3A4 (also CYP2C8), but is also a potent inducer of CYP1A2, CYP3A4 and UDP-glucuronosyltransferases.
* This combination of drugs may have possible synergistic effects. However, the pharmacokinetic drug interactions will influence the plasma levels.
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