| to = agomelatine
| stop =
* '''Before day 1:''' gradually reduce dosage of nortriptyline to a maximum of 50 mg/day, when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of nortriptyline to 25 mg/day.* '''Day 8:''' stop administration of nortriptyline.{{TCAdecrease25p3d}}
| start =
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.* '''Day 8:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. <ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102startAgomelatine}}</ref>
}}
