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* '''Day 1:''' start administration of doxepin the next day in a dosage of 25 mg/day.
* '''Day 2:''' increase dosage of doxepin to 50 mg/day.
* If necessary, increase dosage of doxepin with 25 mg every 2-3 days. <ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>}}
