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Created page with '{{Drugcombi | base = olanzapine | add = quetiapine | info = * Olanzapine is principally metabolized by CYP1A2 and CYP2D6. * Quetiapine is principally metabolized by CYP3A4 to a...'
{{Drugcombi
| base = olanzapine
| add = quetiapine
| info =
* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start quetiapine according to the general dosing advice.
| cave =
* Agents with anticholinergic properties may have additive effects when used in combination. <ref name="drugscom">
{{Drugscominteract|olanzapine-with-quetiapine|olanzapine|quetiapine}}</ref>
}}
| base = olanzapine
| add = quetiapine
| info =
* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start quetiapine according to the general dosing advice.
| cave =
* Agents with anticholinergic properties may have additive effects when used in combination. <ref name="drugscom">
{{Drugscominteract|olanzapine-with-quetiapine|olanzapine|quetiapine}}</ref>
}}
