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Created page with '{{Drugcombi | base = quetiapine | add = gabapentin | info = * Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites. * Gabapentine is eliminated u...'
{{Drugcombi
| base = quetiapine
| add = gabapentin
| info =
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
* Gabapentine is eliminated unchanged by the kidney for 100%.
* This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. <ref name=”freeman”> {{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>
| start =
* Start gabapentine according to the general dosing advice.
| cave =
* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">
{{Drugscominteract|carbamazepine-with-gabapentine|carbamazepine|gabapentine}}</ref>
}}
| base = quetiapine
| add = gabapentin
| info =
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
* Gabapentine is eliminated unchanged by the kidney for 100%.
* This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. <ref name=”freeman”> {{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>
| start =
* Start gabapentine according to the general dosing advice.
| cave =
* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">
{{Drugscominteract|carbamazepine-with-gabapentine|carbamazepine|gabapentine}}</ref>
}}
