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Fluoxetine-moclobemide

257 bytes removed, 14:16, 16 June 2016
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| to = moclobemide
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. {{Generaldecrease25p3d}}* When a dosage of 20 mg/day is reached, stop administration.{{Washoutfluox}}| start = * '''Day 1-28:''' a wash-out period of four weeks is necessary. * '''Day 29:''' start moclobemide the next day in a normal dosage of 300 mg/day.{{MAOIncreasefluox}}| info caveat = * A switch from fluoxetine to moclobemide is not obvious, given the necessary prolonged wash-out period in this case.* Occurrence of serotonin syndrome is reported when a wash-out period (of four weeks) is not considered.| info = * The pharmacologically active metabolite norfluoxetine has a half-life of about 2 weeks.   }}
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