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Created page with '{{Drugswitch | from = fluvoxamine | to = maprotiline | stop = * '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day....'
{{Drugswitch
| from = fluvoxamine
| to = maprotiline
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of maprotiline. If necessary, increase dosage of maprotiline.
| info =
* Fluvoxamine slows the metabolism of imipramine via CYP1A2 and CYP2D6.
* "Start low, go slow" is not required, but caution is necessary.}}
| from = fluvoxamine
| to = maprotiline
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of maprotiline. If necessary, increase dosage of maprotiline.
| info =
* Fluvoxamine slows the metabolism of imipramine via CYP1A2 and CYP2D6.
* "Start low, go slow" is not required, but caution is necessary.}}
