326
edits
Changes
no edit summary
* Gabapentine is eliminated unchanged by the kidney for 100%. Changes in the rate of excretion can cause unwanted effects.
* Topiramate induces CYP3A4 and is an inhibiter of CYP2C19.
* This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects.{{CombiBasic}}
| start =
* Start topiramate according to the general dosing advice.
| cave =
}}
