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Combining-Lithium-Topiramate

174 bytes removed, 15:44, 21 April 2010
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* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* Topiramate induces CYP3A4 and is an inhibiter of CYP2C19.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
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Ashni
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