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Combining-Topiramate-Gabapentin

184 bytes removed, 15:52, 21 April 2010
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* Topiramate induces CYP3A4 and is an inhibiter of CYP2C19.
* Gabapentine is eliminated unchanged by the kidney for 100%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects.
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Ashni
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