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* The combination may rarely cause neurotoxicity ''without increased plasma levels''. <ref> {{Pubmed|8740344|Marcoux AW. Carbamazepine-lithium drug interaction. Ann Pharmacother 1996;30:547}}</ref>
* The combination of these two drugs in generally safe and effective, but it should be avoided for patients with comorbid CNS(central nervous system) disease.<ref''name="freeman''"/ref>
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