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| add = lamotrigine
| info =
* Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases. * {{PossibleSynergisticEffects}}
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* Lamotrigine generally has no significant effect on valproate levels, however caution is recommended.