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| add = risperidone
| info =
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Coadministration with risperidone may alter the serum concentrations of valproic acid, although data are conflicting.