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Combining-Carbamazepine-Aripiprazole

793 bytes added, 15:12, 4 June 2010
Created page with '{{Drugcombi | base = carbamazepine | add = aripiprazole | info = * This combination of drugs may have possible synergistic effects. However, the pharmacokinetic drug interaction...'
{{Drugcombi
| base = carbamazepine
| add = aripiprazole
| info =
* This combination of drugs may have possible synergistic effects. However, the pharmacokinetic drug interactions will influence the plasma levels. Dose adaptation will be recommended for this combination.
| start =
* Coadministration with carbamazepine may decrease the plasma concentrations of aripiprazole via induction of CYP450 3A4.
* Aripiprazole should be given at higher dosage to control psychotic symptoms. <ref name="drugscom">
{{Drugscominteract|aripiprazole-with-carbamazepine-233-0-497-0|aripiprazole|carbamazepine}}</ref>
| cave =
* Pharmacologic response and plasma aripiprazole levels should be monitored more closely whenever carbamazepine is added to or withdrawn from therapy. <ref name="drugscom" />
}}
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