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21:19, 6 June 2010 {{Drugcombi
| base = topiramate
| add = aripiprazole
| info =
* Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start aripiprazole according general dosing advice.
| cave =
* Caution is advised when topiramate is prescribed with other drugs that predispose patients to heat-related disorders, including carbonic anhydrase inhibitors and drugs with anticholinergic activity. <ref name="drugscom">{{DRUGSCOM|risperidone}}</ref>
}}