Changes

* '''Day 0Before day 1:''' If paroxetine dose is above 20mg/day gradually reduce dosage of paroxetine dose to a maximum of 20 mg/day when this dosage is > 20 mg/day. * '''Day 1:''' Reduce dosage of paroxetine to a maximum of 10 mg/day. * '''Day 8:''' reduce dosage Decrease with about 25% of paroxetine to 5 mg/day.original dose every 3-4 days | start = Caution is necessary.* '''Day 81:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day. * '''Day 15Stop paroxetine:''' stop increase administration of paroxetine and only continue nortriptyline in to a dosage of 50 mg/day.* “Start low, go slow” is not required, but caution is necessary.| info = * Paroxetine slows the metabolism of nortriptyline via CYP2D6. * {{SSCYPinh}}* {{TCAplasmalevelmonitoring}}}}