| add = quetiapine
| info =
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
| start =
* Start quetiapine according to the general dosing advice.{{IrrationalCombiAP}}
| cave =
* Quetiapine may have additive adverse cardiovascular effects in combination with other drugs that are known to prolong the QT interval of the electrocardiogram. <ref name="drugscom">
{{Drugscominteract|risperidone-with-quetiapine-2019-13050-1979-12740|risperidone|quetiapine}}</ref>
}}