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* When a dosage of 150 mg/day is reached, stop administration.
| start =
* '''Day 1-3:''' start administration of imipramine the next day in a low dosage of 25 mg/day.
* '''Day 4:''' increase dosage of imipramine to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =
* Bupropion slows the metabolism of imipramine by CYP2D6.
* Caution is necessary at the start of administration of imipramine. }}
