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Created page with '{{Drugswitch | from = duloxetine | to = dosulepine | stop = * '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day. ...'
{{Drugswitch
| from = duloxetine
| to = dosulepine
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.
* '''Day 8:''' stop administration of duloxetine.
| start =
A wash-out period of one week is necessary.
* '''Day 8-14:''' wash-out period.
* '''Day 15:''' start administration of dosulepine in a low dosage of 25-50 mg/day.
| info =
* Duloxetine slows the metabolism of dosulepine by CYP2D6.
* Caution is necessary at the start of administration of dosulepine. }}
| from = duloxetine
| to = dosulepine
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.
* '''Day 8:''' stop administration of duloxetine.
| start =
A wash-out period of one week is necessary.
* '''Day 8-14:''' wash-out period.
* '''Day 15:''' start administration of dosulepine in a low dosage of 25-50 mg/day.
| info =
* Duloxetine slows the metabolism of dosulepine by CYP2D6.
* Caution is necessary at the start of administration of dosulepine. }}
