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* '''Day 7:''' stop administration of vortioxetine.
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* '''Day 8:''' simultaneously start administration of duloxetine in a low normal dosage of 30 -60 mg/day.* '''Day 15:''' increase the dosage of duloxetine to 60 mg/dayif needed.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Duloxetine is a inhibitor of CYP2D6, which metabolizes vortioxetine.}}
