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Duloxetine-tranylcypromine

654 bytes added, 12:50, 4 May 2009
Created page with '{{Drugswitch | from = duloxetine | to = tranylcypromine | stop = * '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 30 mg/ day. When a dosage of 30 mg/day i...'
{{Drugswitch
| from = duloxetine
| to = tranylcypromine
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 30 mg/ day. When a dosage of 30 mg/day is reached, stop administration.
| start =
A wash-out period of one week is necessary.
* '''Day 1-7:''' wash-out period
* '''Day 8-14:''' start tranylcypromine at half the usual dosage for one week.
* '''Day 15:''' start normal dosage of tranylcypromine, 20 mg/day.
| info =
* By considering a wash-out period of one week (5 times the elimination time of duloxetine and its metabolites) it is assured that all duloxetine has left the body and no drug interactions occur. }}
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