| to = agomelatine 
| stop = 
* ''' Day 1:''' Stop hypericum.
* The administration of hypericum can be stopped abruptly.
| start = 
* ''' Day 2: ''' Start administration of agomelatine the next day in agomelatinein a dosage of 25 mg/day.
* If necessary, increase dosage of agomelatine to 50 mg/day. 
 | info = {{reviewnointeractions}}
}}