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Hypericum-moclobemide

47 bytes added, 13:34, 7 October 2015
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* '''Day 15-17:''' a wash-out period of two days is necessary.<ref>{{Pubmed|18294328|Imai H, Kotegawa T, Tsutsumi K, Morimoto T, Eshima N, Nakano S, Ohashi K. The recovery time-course of CYP3A after induction by St John's wort administration. Br J Clin Pharmacol. 2008 May;65(5):701-7.}}</ref><ref>{{Pubmed|16640452|Wurglics M, Schubert-Zsilavecz M. Hypericum perforatum: a 'modern' herbal antidepressant: pharmacokinetics of active ingredients. Clin Pharmacokinet. 2006;45(5):449-68.}}</ref><ref>{{Pubmed|19593191|Derijks HJ, Janknegt R, Heerdink ER, De Koning FH, Krekels MM, Looij BJ, Egberts AC. Influence of antidepressant use on glycemic control in patients with diabetes mellitus: an open-label comparative study. J Clin Psychopharmacol. 2009 Aug;29(4):405-8.}}</ref><ref name="informatorium">{{KNMP|moclobemide}}</ref>
* '''Day 18:''' start moclobemide 150 mg/day.
* '''Day 25: ''' increase meclobemide dosage to 300 mg/day
| caveat =
* Occurrence of the serotonin syndrome is possible without wash-out period.
| info =
{{HypericumInfo}}
 
{{review}}
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