| to = maprotiline
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.{{stopBupropion}}* '''Day 1:''' Stop administration of bupropion| start = {{Inc25p3d2}}* '''Day 1-3:''' start Start administration of maprotiline the next day in a low dosage of 25 mg/day.* '''Day 4:''' increase dosage of maprotiline to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =
* Bupropion slows the metabolism of maprotiline via CYP2D6.
