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Fluoxetine-dosulepine

220 bytes removed, 13:42, 28 October 2015
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| to = dosulepine
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopFluoxetine1}}
| start =
Caution is necessary for at least four weeks.
* '''Day 12:''' start administration of dosulepine in a low dosage of 25 mg/day.* '''Day 1415:''' increase dosage of dosulepine to 50 mg/day.* '''Day 2829:''' increase dosage of dosulepine to 100 mg/day.
| info =
* Fluoxetine and norfluoxetine slow the metabolism of dosulepine via CYP2D6.
* Norfluoxetine has a halflife of at least 1 week: it takes therefore 1 month for elemination.{{longt1/2fluvox}}
* Start low, go slow for dosulepine.
}}
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