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Fluoxetine-doxepine

233 bytes removed, 13:43, 28 October 2015
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| to = doxepin
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopFluoxetine1}}
| start =
Caution is necessary for at least four weeks.
* '''Day 12:''' start administration of doxepin in a low dosage of 25 mg/day.* '''Day 1415:''' increase dosage of doxepin to 50 mg/day.* '''Day 2829:''' increase dosage of doxepin to 75 mg/day.
| info =
* Fluoxetine and norfluoxetine slow the metabolism of doxepin via CYP2D6.
* Norfluoxetine has a halflife of at least 1 week: it takes therefore 1 month for elemination.{{longt1/2fluvox}}
* Start low, go slow for doxepin.
{{review}}}}
Anoek
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